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Senior Principal Application Scientist (m/f/d)

Job ID
495412
Posted since
16-Feb-2026
Organization
Digital Industries
Field of work
Research & Development
Company
Siemens Industry Software GmbH
Experience level
Mid-level Professional
Job type
Full-time
Work mode
Hybrid (Remote/Office)
Employment type
Permanent
Location(s)
  • Frankfurt am Main - - Germany

The role of Principal Application Scientist works with a team of scientists who collaborate with clients through all phases of a project's life cycle. It is part of a cross-functional team with the development and support teams to build new client opportunities, deliver projects, and grow Dotmatics business and scientific reputation. The customers solve complex automated analytical chemistry (chromatography / Mass Spectrometry ) projects across a wide range of laboratory workflows. The role requires self-drive and collaboration as the entire team is remotely based and spread across many time zones, as are our industry partners.

Role Functions:

  • Contribute to business development, project realization, project delivery, and post-delivery training and support activities.
  • Collaborate with clients to understand and capture the scope of existing and new projects.
  • Understand the highly adaptable capabilities of our current solutions and workflows and apply these in the context of new project opportunities. Translate customer-requested functionality and workflow gaps and capture these into project delivery requirements that are understandable to our internal development and support teams.
  • Collaborate with our development team on project customization and core product development.
  • Contribute to the product and automated solution workflow roadmaps of the business.
  • Contribute and help drive our growing scientific and business presence in the industry.
  • Assist our support team in solving more challenging customer support calls and requests.
  • Be a mentor, source of expertise, and communicator, adapting to different levels of technical familiarity with the people with whom we work internally and externally.
  • Travel to and participate in scientific conferences and onsite customer activities.

Skills and Abilities Required:

Overall skills

10+ years of hands-on instrument experience in chromatography and mass spectrometry applications.

Ideally hold a PhD, but open to a Bachelor's Degree or Master's Degree with significant experience in the field/relevant scientific domain, with proven expertise in laboratory workflows.

Prior automation experience, knowledge of Virscidian applications, and familiarity with instrument/robotics hardware are highly desirable.

Advanced analytical skills, problem-solving, great attention to detail, and cross-functional teamwork and communication in all forms of presentation.

 Specific skills  

  • Chromatography and Mass Spectrometry (LC and/or GC).
  • Experience in one or more Analytical Chemistry workflows: Purification, Direct to Biology (D2B), High Throughput Experimentation (HTE), Affinity Screening Studies, or MS-Based DMPK / Bio-assays.
  • Project Management Experience.
  • Working in a global setting.
  • Leading/delivering internal and external meetings and/or training sessions.

You may also have 

  • Familiarity with informatics systems.
  • Prior sales and business development experience.
  • Prior software coding experience or familiarity with a preference in c#